• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

BRL 44408 maleate

CAS No. 681806-46-2

BRL 44408 maleate ( BRL44408;BRL-44408 )

产品货号. M15602 CAS No. 681806-46-2

A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥7857 有现货
50MG ¥16038 有现货
100MG ¥20250 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    BRL 44408 maleate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors.
  • 产品描述
    A potent, selective α2A-adrenoceptor antagonist with Ki of 1.7 nM, 80-fold selectivity over α2B-adrenergic receptors; significantly increases stimulated noradrenaline release in rat locus coeruleus slices at 0.1-1 uM, significantly increases the electrically induced release in rats.
  • 同义词
    BRL44408;BRL-44408
  • 通路
    Angiogenesis
  • 靶点
    Adrenergic Receptor
  • 受体
    Adrenergic Receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    681806-46-2
  • 分子量
    331.37
  • 分子式
    C17H21N3O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC1N(CC2=NCCN2)CC3=C1C=CC=C3.O=C(O)/C=C\C(O)=O
  • 化学全称
    2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Kiss JP, et al. Brain Res. 1995 Mar 20;674(2):238-44.
2. Callado LF, et al. Eur J Pharmacol. 1999 Jan 29;366(1):35-9.
3. Young P, et al. Eur J Pharmacol. 1989 Sep 22;168(3):381-6.
产品手册
关联产品
  • Medetomidine hydroch...

    A potent, highly selective α2-adrenoceptor agonist with Ki of 1.08 nM; used as both a surgical anesthetic and analgesic.

  • Rec 15/2615 dihydroc...

    Rec 15/2615 dihydrochloride is an antagonist of α1B-adrenergic receptor.

  • Acebutolol

    A cardioselective beta blocker for the treatment of hypertension and arrhythmias.